Licensed from medwireNews with authorization from Springer Health care Ltd. All rights reserved. Neither of the parties endorse or recommend any commercial products, services, or equipment.. Adolescents with psychosis encounter long treatment delays By Lucy Piper, Senior medwireNews Reporter Adolescents have a duration of untreated psychosis that is approximately twice that seen in adults, UK research findings show. Factors associated with this lengthy DUP include Light ethnicity, younger age group of onset, and lifetime cannabis use. White adolescents also had the best rate of cannabis make use of, at 76. The results suggest a need for physicians to be vigilant when managing and identifying psychosis in adolescents, says the team of researchers, led by Maria-de-Gracia Dominguez . These individuals experienced a median DUP of 179 times versus 81 days for the 804 individuals with adult-onset psychosis.Paired-end DNA libraries from bone marrow samples and normal pores and skin samples had been sequenced on the Illumina HiSeq 2000 and Genome Analyzer IIx. Aligned reads had been analyzed to detect putative somatic mutations, as defined previously.16 Somatic-mutation predictions were validated by using solid-phase capture, followed by deep sequencing of epidermis, myelodysplastic-syndrome, and secondary-AML samples. Mutations in a single subject matter have been reported previously.17 Array-based profiling of DNA duplicate amount and gene expression were performed, as described previously.18 Sequence and microarray data have already been deposited in the data source of Genotypes and Phenotypes of the National Center for Biotechnology Information .